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Professor Anna Dominiczak (pubs from 1996)

Genome-wide association study identifies novel genes for biomarkers of cardiovascular disease: serum urate and dyslipidemia
Am J Hum Genet. 2008 Jan 10; 82(1) pp. 139 - 149
Chris Wallace; Stephen J Newhouse; Peter Braund; Feng Zhang; Martin Tobin; Mario Falchi; Kourosh Ahmadi; Richard J Dobson; Ana Carolina B Marçano; Cother Hajat; Paul Burton; Panagiotis Deloukas; Morris Brown; John M Connell; Anna Dominiczak; G Mark Lathrop; John Webster; The Wellcome Trust Case Control Consortium; Martin Farrall; Tim Spector; Nilesh J Samani; Mark J Caulfield; Patricia B. Munroe

Genomewide association analysis of coronary artery disease.
N Engl J Med. 2007 Aug 2;357(5):443-53. Epub 2007 Jul 18.
Samani NJ, Erdmann J, Hall AS, Hengstenberg C, Mangino M, Mayer B, Dixon RJ, Meitinger T, Braund P, Wichmann HE, Barrett JH, König IR, Stevens SE, Szymczak S, Tregouet DA, Iles MM, Pahlke F, Pollard H, Lieb W, Cambien F, Fischer M, Ouwehand W, Blankenberg S, Balmforth AJ, Baessler A, Ball SG, Strom TM, Braenne I, Gieger C, Deloukas P, Tobin MD, Ziegler A, Thompson JR, Schunkert H, WTCCC

Genetic association analysis of inositol polyphosphate phosphatase-like 1 (INPPL1, SHIP2) variants with essential hypertension.
J Med Genet. 2007 Jun 8; [Epub ahead of print]
Braga Marcano AC, Burke B, Gungadoo J, Wallace C, Kaisaki PJ, Woon PY, Farrall M, Clayton D, Brown M, Dominiczak A, Connell JM, Webster J, Lathrop M, Caulfield M, Samani N, Gauguier D, Munroe PB.

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.
Nature. 2007 Jun 7;447(7145):661-78.
Wellcome Trust Case Control Consortium.

Chris Wallace, Ming-Zhan Xue, Stephen J. Newhouse, Ana Carolina B. Marçano, Abiodun K. Onipinla, Beverley Burke, Johannie Gungadoo, Richard J. Dobson, Morris Brown, John M. Connell, Anna Dominiczak, G. Mark Lathrop, John Webster, Martin Farrall, Charles Mein, Nilesh J. Samani, Mark J. Caulfield, David G. Clayton, and Patricia B. Munroe
Linkage Analysis Using Co-Phenotypes in the BRIGHT Study Reveals Novel Potential Susceptibility Loci for Hypertension.
Am J Hum Genet. 2006 Aug;79(2):323-31. Epub 2006 Jun 19.

Munroe PB, Wallace C, Xue MZ, B Marcano AC, Dobson RJ, Onipinla AK, Burke B, Gungadoo J, Newhouse SJ, Pembroke J, Brown M, Dominiczak AF, Samani NJ, Lathrop M, Connell J, Webster J, Clayton D, Farrall M, Mein CA, Caulfield M Increased Support for Linkage of a Novel Locus on Chromosome 5q13 for Essential Hypertension in the British Genetics of Hypertension Study.
Hypertension. 2006 Jun 5; [Epub ahead of print]

Bell JT, Wallace C, Dobson R, Wiltshire S, Mein C, Pembroke J, Brown M, Clayton D, Samani N, Dominiczak A, Webster J, Lathrop GM, Connell J, Munroe P, Caulfield M, Farrall M.
Two-dimensional genome-scan identifies novel epistatic loci for essential hypertension.
Hum Mol Genet. 2006 Apr 15;15(8):1365-74. Epub 2006 Mar 16

Sandosh Padmanabhan PhD, Chris Wallace Ph.D, Patricia B. Munroe Ph.D, Richard Dobson BSc, Morris Brown F.R.C.P, Nilesh Samani F.R.C.P, David Clayton B.A, Martin Farrall FRCPath, John Webster F.R.C.P, Mark Lathrop Ph.D, Mark Caulfield F.R.C.P, Anna F. Dominiczak F.R.C.P, John M. Connell F.R.C.P.
Chromosome 2p shows significant linkage to anti-hypertensive response in the British Genetics of Hypertension (BRIGHT) study.
Hypertension. 2006 Mar;47(3):603-8. Epub 2006 Jan 3.

Al Benna S, Hamilton CA, McClure JD, Rogers PN, Berg GA, Ford I, Delles C, Dominiczak AF.
Low-density lipoprotein cholesterol determines oxidative stress and endothelial dysfunction in saphenous veins from patients with coronary artery disease.
Arterioscler Thromb Vasc Biol 2006;26:218-223.

Ibrahim J, McGee A, Graham D, McGrath JC, Dominiczak AF.
Sex-specific differences in cerebral arterial myogenic tone in hypertensive and normotensive rats.
Am J Physiol Heart Circ Physiol 2006;290:H1081-H1089.

McBride MW, Graham D, Delles C, Dominiczak AF.
Functional genomics in hypertension.
Curr Opin Nephrol Hypertens 2006;15:145-151.

S.J. Newhouse, C. Wallace, R. Dobson, C. Mein, J. Pembroke, M. Farrall, D. Clayton, M. Brown, N. Samani, A. Dominiczak, J.M. Connell, J. Webster, G.M. Lathrop, M. Caulfield, P. B. Munroe.
Haplotypes of the WNK1 gene associate with blood pressure variation in a severely hypertensive population from the British Genetics of Hypertension (BRIGHT) study.
Human Molecular Genetics. Jul 1;14(13):1805-14. Epub 2005 May 11.

Brain N, Jr., Dominiczak AF.
Pharmacogenomics in hypertension: present practicalities and future potential.
J Hypertens 2005;23:1327-1329.

Carswell HV, Dominiczak AF, Garcia-Segura LM, Harada N, Hutchison JB, Macrae IM.
Brain aromatase expression after experimental stroke: topography and time course.
J Steroid Biochem Mol Biol 2005;96:89-91.

Carswell HV, McBride MW, Graham D, Dominiczak AF, Macrae IM.
Mutant animal models of stroke and gene expression: the stroke-prone spontaneously hypertensive rat.
Methods Mol Med 2005;104:49-74.

Collison M, James DJ, Graham D, Holman GD, Connell JM, Dominiczak AF, Gould GW, Salt IP.
Reduced insulin-stimulated GLUT4 bioavailability in stroke-prone spontaneously hypertensive rats.
Diabetologia 2005;48:539-546.

Dominiczak AF, Graham D, McBride MW, Brain NJ, Lee WK, Charchar FJ, Tomaszewski M, Delles C, Hamilton CA.
Corcoran Lecture. Cardiovascular genomics and oxidative stress.
Hypertension 2005;45:636-642.

Graham D, McBride MW, Brain NJ, Dominiczak AF. Congenic/consomic models of hypertension.
Methods Mol Med 2005;108:3-15.

McBride MW, Brosnan MJ, Mathers J, McLellan LI, Miller WH, Graham D, Hanlon N, Hamilton CA, Polke JM, Lee WK, Dominiczak AF.
Reduction of Gstm1 expression in the stroke-prone spontaneously hypertension rat contributes to increased oxidative stress.
Hypertension 2005;45:786-792.

McCallum RW, Sainsbury CA, Spiers A, Dominiczak AF, Petrie JR, Sattar N, Connell JM.
Growth hormone replacement reduces C-reactive protein and large-artery stiffness but does not alter endothelial function in patients with adult growth hormone deficiency.
Clin Endocrinol (Oxf) 2005;62:473-479.

McCallum RW, Hamilton CA, Graham D, Jardine E, Connell JM, Dominiczak AF.
Vascular responses to IGF-I and insulin are impaired in aortae of hypertensive rats.
J Hypertens 2005;23:351-358.

McGill JK, Gallagher L, Carswell HV, Irving EA, Dominiczak AF, Macrae IM.
Impaired functional recovery after stroke in the stroke-prone spontaneously hypertensive rat.
Stroke 2005;36:135-141.

Miller WH, Brosnan MJ, Graham D, Nicol CG, Morecroft I, Channon KM, Danilov SM, Reynolds PN, Baker AH, Dominiczak AF.
Targeting endothelial cells with adenovirus expressing nitric oxide synthase prevents elevation of blood pressure in stroke-prone spontaneously hypertensive rats.
Mol Ther 2005;12:321-327.

Nemoto K, Sekimoto M, Fukamachi K, Kageyama H, Degawa M, Hamadai M, Hendley ED, Macrae IM, Clark JS, Dominiczak AF, Ueyama T.
No involvement of the nerve growth factor gene locus in hypertension in spontaneously hypertensive rats.
Hypertens Res 2005;28:155-163.

Strahorn P, Graham D, Charchar FJ, Sattar N, McBride MW, Dominiczak AF.
Genetic determinants of metabolic syndrome components in the stroke-prone spontaneously hypertensive rat.
J Hypertens 2005;23:2179-2186.

Tomaszewski M, Charchar FJ, Zukowska-Szczechowska E, Grzeszczak W, Dominiczak AF.
Letter re: Inflammation and lipoprotein changes with protracted exercise.
J Clin Endocrinol Metab 2005;90:4981.

Antier D, Carswell HV, Brosnan MJ, Hamilton CA, Macrae IM, Groves S, Jardine E, Reid JL, Dominiczak AE.
Increased levels of superoxide in brains from old female rats.
Free Radic Res 2004;38:177-183.

Carswell HV, Bingham D, Wallace K, Nilsen M, Graham DI, Dominiczak AF, Macrae IM.
Differential effects of 17beta-estradiol upon stroke damage in stroke prone and normotensive rats.
J Cereb Blood Flow Metab 2004;24:298-304.

Dominiczak AF, Brain N, Charchar F, McBride M, Hanlon N, Lee WK.
Genetics of hypertension: lessons learnt from mendelian and polygenic syndromes.
Clin Exp Hypertens 2004;26:611-620.

Graham D, Hamilton C, Beattie E, Spiers A, Dominiczak AF.
Comparison of the effects of omapatrilat and irbesartan/hydrochlorothiazide on endothelial function and cardiac hypertrophy in the stroke-prone spontaneously hypertensive rat: sex differences.
J Hypertens 2004;22:329-337.

Graham D, McBride MW, Brain NJ, Dominiczak AF.
Congenic/Consomic models of hypertension.
Methods Mol Med 2004;108:3-16.

Hunt E, Hanlon N, Leader DP, Bryce H, Dominiczak AF.
The visual language of synteny.
OMICS 2004;8:289-305.

Kuznetsova T, Staessen JA, Stolarz K, Ryabikov A, Tikhonoff V, Olszanecka A, Bianchi G, Brand E, Casiglia E, Dominiczak A, Fagard R, Malyutina S, Nikitin Y, Kawecka-Jaszcz K.
Relationship between left ventricular mass and the ACE D/I polymorphism varies according to sodium intake.
J Hypertens 2004;22:287-295.

Tomaszewski M, Charchar FJ, Crawford L, Zukowska-Sczechowska E, Grzeszczak W, Sattar N, Dominiczak AF.
Serum C-reactive protein and lipids in ultra-Marathon runners.
Am J Cardiol 2004;94:125-126.

Tomaszewski M, Charchar FJ, Lacka B, Pesonen U, Wang WY, Zukowska-Szczechowska E, Grzeszczak W, Dominiczak AF.
Epistatic interaction between beta2-adrenergic receptor and neuropeptide Y genes influences LDL-cholesterol in hypertension.
Hypertension 2004;44:689-694.

Hamilton CA, Miller WH, Al-Benna S, Brosnan MJ, Drummond RD, McBride MW, Dominiczak AF.
Strategies to reduce oxidative stress in cardiovascular disease. Clin Sci (Lond). 2004 Mar;106(3):219-34.

Charchar FJ, Tomaszewski M, Lacka B, Zakrzewski J, Zukowska-Szczechowska E, Grzeszczak W, Dominiczak AF.
Association of the human Y chromosome with cholesterol levels in the general population.
Arterioscler Thromb Vasc Biol. 2004 Feb;24(2):308-12.

McBride MW, Charchar FJ, Graham D, Miller WH, Strahorn P, Carr FJ, Dominiczak AF.
Functional genomics in rodent models of hypertension.
J Physiol. 2004 Jan 1;554(Pt 1):56-63. Review.

McBride MW, Charchar FJ, Graham D, Miller WH, Strahorn P, Carr FJ, Dominiczak AF.
Functional genomics in rodent models of hypertension.
J Physiol. 2003 Oct 17

Dominiczak AF, McBride MW.
Genetics of common polygenic stroke.
Nat Genet. 2003 Oct;35(2):116-7

Pell JP, Smith GC, Dominiczak A, Cobbe SM, Dobbie R, McMahon AD, Ford I.
Family history of premature death from ischaemic heart disease is associated with an increased risk of delivering a low birth weight baby.
Heart. 2003 Oct;89(10):1249-50.

Tomaszewski M, Charchar FJ, Przybycin M, Crawford L, Wallace AM, Gosek K, Lowe GD, Zukowska-Szczechowska E, Grzeszczak W, Sattar N, Dominiczak AF.
Strikingly low circulating CRP concentrations in ultramarathon runners independent of markers of adiposity: how low can you go? Arterioscler Thromb Vasc Biol. 2003 Sep 1;23(9):1640-4.

Caulfield M, Munroe P, Pembroke J, Samani N, Dominiczak A, Brown M, Benjamin N, Webster J, Ratcliffe P, O'Shea S, Papp J, Taylor E, Dobson R, Knight J, Newhouse S, Hooper J, Lee W, Brain N, Clayton D, Lathrop GM, Farrall M, Connell J; MRC British Genetics of Hypertension Study.
Genome-wide mapping of human loci for essential hypertension. Lancet. 2003 Jun 21;361(9375):2118-23.

Izzard AS, Graham D, Burnham MP, Heerkens EH, Dominiczak AF, Heagerty AM.
Myogenic and structural properties of cerebral arteries from the stroke-prone spontaneously hypertensive rat.
Am J Physiol Heart Circ Physiol. 2003 Oct;285(4):H1489-94.

Tomaszewski M, Charchar FJ, Padmanabhan S, Zukowska-Szczechowska E, Grzeszczak W, Dominiczak AF.
Cardiovascular diseases and G-protein beta3 subunit gene (GNB3) in the era of genomewide scans.
J Hum Hypertens. 2003 Jun;17(6):379-80.

Charchar FJ, Tomaszewski M, Strahorn P, Champagne B, Dominiczak AF.
Y is there a risk to being male?
Trends Endocrinol Metab. 2003 May-Jun;14(4):163-8. Review.

McBride MW, Carr FJ, Graham D, Anderson NH, Clark JS, Lee WK, Charchar FJ, Brosnan MJ, Dominiczak AF.
Microarray analysis of rat chromosome 2 congenic strains. Hypertension. 2003 Mar;41(3 Pt 2):847-53. Erratum in: Hypertension. 2003 May 5;41(6):e13.

Brown MJ, Cruickshank JK, Dominiczak AF, MacGregor GA, Poulter NR, Russell GI, Thom S, Williams B; Executive Committee, British Hypertension Society.
Better blood pressure control: how to combine drugs.
J Hum Hypertens. 2003 Feb;17(2):81-6. Review

Khan IY, Taylor PD, Dekou V, Seed PT, Lakasing L, Graham D, Dominiczak AF, Hanson MA, Poston L.
Gender-linked hypertension in offspring of lard-fed pregnant rats. Hypertension. 2003 Jan;41(1):168-75.

Stanton T, Inglis GC, Padmanabhan S, Dominiczak AF, Jardine AG, Connell JM.
Variation at the beta-1 adrenoceptor gene locus affects left ventricular mass in renal failure.
J Nephrol. 2002 Sep-Oct;15(5):512-8.

Hamilton CA, Brosnan MJ, Al-Benna S, Berg G, Dominiczak AF. NAD(P)H oxidase inhibition improves endothelial function in rat and human blood vessels.
Hypertension. 2002 Nov;40(5):755-62.

Tomaszewski M, Brain NJ, Charchar FJ, Wang WY, Lacka B, Padmanabahn S, Clark JS, Anderson NH, Edwards HV, Zukowska-Szczechowska E, Grzeszczak W, Dominiczak AF.
Essential hypertension and beta2-adrenergic receptor gene: linkage and association analysis.
Hypertension. 2002 Sep;40(3):286-91.

Carr FJ, McBride MW, Carswell HV, Graham D, Strahorn P, Clark JS, Charchar FJ, Dominiczak AF.
Genetic aspects of stroke: human and experimental studies.
J Cereb Blood Flow Metab. 2002 Jul;22(7):767-73.

McCallum RW, Petrie JR, Dominiczak AF, Connell JM.
Growth hormone deficiency and vascular risk.
Clin Endocrinol (Oxf). 2002 Jul;57(1):11-24.

Duncan AC, Petrie JR, Brosnan MJ, Devlin AM, Bass RA, Charnock-Jones DS, Connell JM, Dominiczak AF, Lumsden MA.
Is estradiol cardioprotection a nitric oxide-mediated effect?
Hum Reprod. 2002 Jul;17(7):1918-24.

Carr FJ, Negrin CD, Clark JS, Graham D, McBride MW, Anderson NW, Dominiczak AF.
Chromosome 2 reciprocal congenic strains to evaluate the effect of the genetic background on blood pressure.
Scott Med J. 2002 Feb;47(1):7-9.

McBride MW, Carswell HV, Graham D, Carr FJ, Charchar FJ, Macrae IM, Dominiczak AF.
Genetic and gender determinants of cerebrovascular disease. Semin Nephrol. 2002 Mar;22(2):127-34.

Charchar FJ, Tomaszewski M, Padmanabhan S, Lacka B, Upton MN, Inglis GC, Anderson NH, McConnachie A, Zukowska-Szczechowska E, Grzeszczak W, Connell JM, Watt GC, Dominiczak AF.
The Y chromosome effect on blood pressure in two European populations.
Hypertension. 2002 Feb;39(2 Pt 2):353-6.

Fennell JP, Brosnan MJ, Frater AJ, Hamilton CA, Alexander MY, Nicklin SA, Heistad DD, Baker AH, Dominiczak AF.
Adenovirus-mediated overexpression of extracellular superoxide dismutase improves endothelial dysfunction in a rat model of hypertension.
Gene Ther. 2002 Jan;9(2):110-7.

Hamilton CA, O'Dowd G, McIntosh L, Berg G, Butler J, Pathi V, Williams R, Reid JL, Dominiczak AF.
Vasorelaxant properties of isolated human radial arteries: comparison with internal mammary arteries.
Atherosclerosis. 2002 Feb;160(2):345-53.

Brosnan MJ, Hamilton CA, Graham D, Lygate CA, Jardine E, Dominiczak AF.
Irbesartan lowers superoxide levels and increases nitric oxide bioavailability in blood vessels from spontaneously hypertensive stroke-prone rats.
J Hypertens. 2002 Feb;20(2):281-6.

Nicklin SA, Von Seggern DJ, Work LM, Pek DC, Dominiczak AF, Nemerow GR, Baker AH.
Ablating adenovirus type 5 fiber-CAR binding and HI loop insertion of the SIGYPLP peptide generate an endothelial cell-selective adenovirus.
Mol Ther. 2001 Dec;4(6):534-42.

Dorrance AM, Graham D, Webb RC, Fraser R, Dominiczak A. Increased membrane sphingomyelin and arachidonic acid in stroke-prone spontaneously hypertensive rats.
Am J Hypertens. 2001 Nov;14(11 Pt 1):1149-53.

Cohuet G, Challande P, Osborne-Pellegrin M, Arribas SM, Dominiczak A, Louis H, Laurent S, Lacolley P.
Mechanical strength of the isolated carotid artery in SHR. Hypertension. 2001 Nov;38(5):1167-71.

Berry C, Touyz R, Dominiczak AF, Webb RC, Johns DG.
Angiotensin receptors: signaling, vascular pathophysiology, and interactions with ceramide.
Am J Physiol Heart Circ Physiol. 2001 Dec;281(6):H2337-65.

James DJ, Cairns F, Salt IP, Murphy GJ, Dominiczak AF, Connell JM, Gould GW.
Skeletal muscle of stroke-prone spontaneously hypertensive rats exhibits reduced insulin-stimulated glucose transport and elevated levels of caveolin and flotillin.
Diabetes. 2001 Sep;50(9):2148-56.

Petrie JR, Collison M, Connell JM, Gould GW, Dominiczak AF. CD36 deficiency and insulin resistance.
Lancet. 2001 Jul 21;358(9277):242-3.

Marks L, Carswell HV, Peters EE, Graham DI, Patterson J, Dominiczak AF, Macrae IM.
Characterization of the microglial response to cerebral ischemia in the stroke-prone spontaneously hypertensive rat.
Hypertension. 2001 Jul;38(1):116-22.

Nicklin SA, Reynolds PN, Brosnan MJ, White SJ, Curiel DT, Dominiczak AF, Baker AH.
Analysis of cell-specific promoters for viral gene therapy targeted at the vascular endothelium.
Hypertension. 2001 Jul;38(1):65-70.

Zicha J, Negrin CD, Dobesova Z, Carr F, Vokurkova M, McBride MW, Kunes J, Dominiczak AF.
Altered Na+-K+ pump activity and plasma lipids in salt-hypertensive Dahl rats: relationship to Atp1a1 gene.
Physiol Genomics. 2001 Jul 17;6(2):99-104.

Berry C, Anderson N, Kirk AJ, Dominiczak AF, McMurray JJ. Renin angiotensin system inhibition is associated with reduced free radical concentrations in arteries of patients with coronary heart disease.
Heart. 2001 Aug;86(2):217-20.

Jamieson A, Ingham DG, Dominiczak AF, Connell JM.
Not the usual cause of superior vena cava obstruction.
Scott Med J. 2001 Apr;46(2):51-2.

Hamilton CA, McPhaden AR, Berg G, Pathi V, Dominiczak AF.
Is hydrogen peroxide an EDHF in human radial arteries?
Am J Physiol Heart Circ Physiol. 2001 Jun;280(6):H2451-5.

De Lange RP, Burr K, Clark JS, Negrin CD, Brosnan MJ, St Clair DM, Dominiczak AF, Shaw DJ.
Mapping and sequencing rat dishevelled-1: a candidate gene for cerebral ischaemic insult in a rat model of stroke.
Neurogenetics. 2001 Mar;3(2):99-106.

MacKay AJ, Hamilton CA, McArthur K, Berg G, Tropeano AI, Boutouyrie P, Reid JL, Dominiczak AF.
Radial artery hypertrophy occurs in coronary atherosclerosis and is independent of blood pressure.
Clin Sci (Lond). 2001 May;100(5):509-16.

Hamilton CA, Brosnan MJ, McIntyre M, Graham D, Dominiczak AF.
Superoxide excess in hypertension and aging: a common cause of endothelial dysfunction.
Hypertension. 2001 Feb;37(2 Part 2):529-34.

Negrin CD, McBride MW, Carswell HV, Graham D, Carr FJ, Clark JS, Jeffs B, Anderson NH, Macrae IM, Dominiczak AF.
Reciprocal consomic strains to evaluate y chromosome effects. Hypertension. 2001 Feb;37(2 Part 2):391-7.

Berry C, Brosnan MJ, Fennell J, Hamilton CA, Dominiczak AF. Oxidative stress and vascular damage in hypertension.
Curr Opin Nephrol Hypertens. 2001 Mar;10(2):247-55.

MacKenzie CJ, Wakefield JM, Cairns F, Dominiczak AF, Gould GW.
Regulation of glucose transport in aortic smooth muscle cells by cAMP and cGMP.
Biochem J. 2001 Feb 1;353(Pt 3):513-9.

Collison M, Campbell IW, Salt IP, Dominiczak AF, Connell JM, Lyall H, Gould GW.
Sex hormones induce insulin resistance in 3T3-L1 adipocytes by reducing cellular content of IRS proteins.
Diabetologia. 2000 Nov;43(11):1374-80.

Collison M, Glazier AM, Graham D, Morton JJ, Dominiczak MH, Aitman TJ, Connell JM, Gould GW, Dominiczak AF.
Cd36 and molecular mechanisms of insulin resistance in the stroke-prone spontaneously hypertensive rat.
Diabetes. 2000 Dec;49(12):2222-6.

Lee WK, Padmanabhan S, Dominiczak AF.
Genetics of hypertension: from experimental models to clinical applications.
J Hum Hypertens. 2000 Oct-Nov;14(10-11):631-47.

McLauren Dorrance A, Graham D, Dominiczak A, Fraser R. Inhibition of nitric oxide synthesis increases erythrocyte membrane fluidity and unsaturated fatty acid content.
Am J Hypertens. 2000 Nov;13(11):1194-202.

Alexander MY, Brosnan MJ, Hamilton CA, Fennell JP, Beattie EC, Jardine E, Heistad DD, Dominiczak AF.
Gene transfer of endothelial nitric oxide synthase but not Cu/Zn superoxide dismutase restores nitric oxide availability in the SHRSP.
Cardiovasc Res. 2000 Aug 18;47(3):609-17.

Devlin AM, Clark JS, Reid JL, Dominiczak AF.
DNA synthesis and apoptosis in smooth muscle cells from a model of genetic hypertension.
Hypertension. 2000 Jul;36(1):110-5.

Carswell HV, Anderson NH, Morton JJ, McCulloch J, Dominiczak AF, Macrae IM.
Investigation of estrogen status and increased stroke sensitivity on cerebral blood flow after a focal ischemic insult.
J Cereb Blood Flow Metab. 2000 Jun;20(6):931-6.

Berry C, Hamilton CA, Brosnan MJ, Magill FG, Berg GA, McMurray JJ, Dominiczak AF.
Investigation into the sources of superoxide in human blood vessels: angiotensin II increases superoxide production in human internal mammary arteries.
Circulation. 2000 May 9;101(18):2206-12.

Alexander MY, Brosnan MJ, Hamilton CA, Downie P, Devlin AM, Dowell F, Martin W, Prentice HM, O'Brien T, Dominiczak AF.
Gene transfer of endothelial nitric oxide synthase improves nitric oxide-dependent endothelial function in a hypertensive rat model. Cardiovasc Res. 1999 Aug 15;43(3):798-807.

Orlov SN, Adarichev VA, Devlin AM, Maximova NV, Sun YL, Tremblay J, Dominiczak AF, Postnov YV, Hamet P.
Increased Na(+)/H(+) exchanger isoform 1 activity in spontaneously hypertensive rats: lack of mutations within the coding region of NHE1.
Biochim Biophys Acta. 2000 Feb 21;1500(2):169-80.

Carswell HV, Dominiczak AF, Macrae IM.
Estrogen status affects sensitivity to focal cerebral ischemia in stroke-prone spontaneously hypertensive rats.
Am J Physiol Heart Circ Physiol. 2000 Jan;278(1):H290-4.

Jeffs B, Negrin CD, Graham D, Clark JS, Anderson NH, Gauguier D, Dominiczak AF.
Applicability of a "speed" congenic strategy to dissect blood pressure quantitative trait loci on rat chromosome 2.
Hypertension. 2000 Jan;35(1 Pt 2):179-87.

Dominiczak AF, Negrin DC, Clark JS, Brosnan MJ, McBride MW, Alexander MY.
Genes and hypertension: from gene mapping in experimental models to vascular gene transfer strategies.
Hypertension. 2000 Jan;35(1 Pt 2):164-72.

McIntyre M, Bohr DF, Dominiczak AF.
Endothelial function in hypertension: the role of superoxide anion. Hypertension. 1999 Oct;34(4 Pt 1):539-45.

Dowell FJ, Martin W, Dominiczak AF, Hamilton CA.
Decreased basal despite enhanced agonist-stimulated effects of nitric oxide in 12-week-old stroke-prone spontaneously hypertensive rat.
Eur J Pharmacol. 1999 Aug 27;379(2-3):175-82.

Hamilton CA, Williams R, Pathi V, Berg G, McArthur K, McPhaden AR, Reid JL, Dominiczak AF.
Pharmacological characterisation of endothelium-dependent relaxation in human radial artery: comparison with internal thoracic artery.
Cardiovasc Res. 1999 Apr;42(1):214-23.

Brosnan MJ, Devlin AM, Clark JS, Mullins JJ, Dominiczak AF.
Different effects of antihypertensive agents on cardiac and vascular hypertrophy in the transgenic rat line TGR(mRen2)27.
Am J Hypertens. 1999 Jul;12(7):724-31.

Kerr S, Brosnan MJ, McIntyre M, Reid JL, Dominiczak AF, Hamilton CA.
Superoxide anion production is increased in a model of genetic hypertension: role of the endothelium.
Hypertension. 1999 Jun;33(6):1353-8.

Hamilton CA, Berg G, McArthur K, Reid JL, Dominiczak AF.
Does potassium channel opening contribute to endothelium-dependent relaxation in human internal thoracic artery?
Clin Sci (Lond). 1999 Jun;96(6):631-8.

Carswell HV, Anderson NH, Clark JS, Graham D, Jeffs B, Dominiczak AF, Macrae IM.
Genetic and gender influences on sensitivity to focal cerebral ischemia in the stroke-prone spontaneously hypertensive rat. Hypertension. 1999 Feb;33(2):681-5.

Brosnan MJ, Clark JS, Jeffs B, Negrin CD, Van Vooren P, Arribas SM, Carswell H, Aitman TJ, Szpirer C, Macrae IM, Dominiczak AF.
Genes encoding atrial and brain natriuretic peptides as candidates for sensitivity to brain ischemia in stroke-prone hypertensive rats. Hypertension. 1999 Jan;33(1 Pt 2):290-7.

Anderson NH, Devlin AM, Graham D, Morton JJ, Hamilton CA, Reid JL, Schork NJ, Dominiczak AF.
Telemetry for cardiovascular monitoring in a pharmacological study: new approaches to data analysis.
Hypertension. 1999 Jan;33(1 Pt 2):248-55.

Dominiczak AF, Clark JS, Jeffs B, Anderson NH, Negrin CD, Lee WK, Brosnan MJ.
Genetics of experimental hypertension.
J Hypertens. 1998 Dec;16(12 Pt 2):1859-69.

Dominiczak AF, Jeffs B, Connell JM.
New genetic concepts in hypertensive cardiovascular disease.
Curr Opin Cardiol. 1998 Sep;13(5):304-11.

Lee WK, Haddad L, Macleod MJ, Dorrance AM, Wilson DJ, Gaffney D, Dominiczak MH, Packard CJ, Day IN, Humphries SE, Dominiczak AF.
Identification of a common low density lipoprotein receptor mutation (C163Y) in the west of Scotland.
J Med Genet. 1998 Jul;35(7):573-8.

Webster J, Marshall F, Abdalla M, Dominiczak A, Edwards R, Isles CG, Loose H, Main J, Padfield P, Russell IT, Walker B, Watson M, Wilkinson R.
Randomised comparison of percutaneous angioplasty vs continued medical therapy for hypertensive patients with atheromatous renal artery stenosis.
Scottish and Newcastle Renal Artery Stenosis Collaborative Group. J Hum Hypertens. 1998 May;12(5):329-35.

Makin AP, McIntyre M, Pace N, Akyol M, Dominiczak AF.
Resection of phaeochromocytoma at 16-weeks gestation.
Eur J Anaesthesiol. 1998 Jan;15(1):118-21.

Gratton JA, Sauter A, Rudin M, Lees KR, McColl J, Reid JL, Dominiczak AF, Macrae IM.
Susceptibility to cerebral infarction in the stroke-prone spontaneously hypertensive rat is inherited as a dominant trait. Stroke. 1998 Mar;29(3):690-4

McIntyre M, Dominiczak AF.
Nitric oxide and cardiovascular disease.
Postgrad Med J. 1997 Oct;73(864):630-4.

Arribas SM, Gonzalez C, Graham D, Dominiczak AF, McGrath JC. Cellular changes induced by chronic nitric oxide inhibition in intact rat basilar arteries revealed by confocal microscopy.
J Hypertens. 1997 Dec;15(12 Pt 2):1685-93.

Devlin AM, Brosnan MJ, Graham D, Morton JJ, McPhaden AR, McIntyre M, Hamilton CA, Reid JL, Dominiczak AF.
Vascular smooth muscle cell polyploidy and cardiomyocyte hypertrophy due to chronic NOS inhibition in vivo.
Am J Physiol. 1998 Jan;274(1 Pt 2):H52-9.

Dominiczak AF, Devlin AM, Brosnan MJ, Anderson NH, Graham D, Clark JS, McPhaden A, Hamilton CA, Reid JL.
Left ventricular hypertrophy and arterial blood pressure in experimental models of hypertension.
Adv Exp Med Biol. 1997;432:23-33.

McIntyre M, Hamilton CA, Rees DD, Reid JL, Dominiczak AF.
Sex differences in the abundance of endothelial nitric oxide in a model of genetic hypertension.
Hypertension. 1997 Dec;30(6):1517-24.

Arribas SM, Hillier C, Gonzalez C, McGrory S, Dominiczak AF, McGrath JC.
Cellular aspects of vascular remodeling in hypertension revealed by confocal microscopy.
Hypertension. 1997 Dec;30(6):1455-64.

Hamilton CA, Berg G, Mcintyre M, Mcphaden AR, Reid JL, Dominiczak AF.
Effects of nitric oxide and superoxide on relaxation in human artery and vein.
Atherosclerosis. 1997 Aug;133(1):77-86.

Jeffs B, Clark JS, Anderson NH, Gratton J, Brosnan MJ, Gauguier D, Reid JL, Macrae IM, Dominiczak AF.
Sensitivity to cerebral ischaemic insult in a rat model of stroke is determined by a single genetic locus.
Nat Genet. 1997 Aug;16(4):364-7.

Dominiczak AF, McIntyre M, Rees D, Hamilton CA, Reid JL. Estrogen effects on nitric oxide release.
Hypertension. 1997 Jun;29(6):1357.

Harden PN, MacLeod MJ, Rodger RS, Baxter GM, Connell JM, Dominiczak AF, Junor BJ, Briggs JD, Moss JG.
Effect of renal-artery stenting on progression of renovascular renal failure.
Lancet. 1997 Apr 19;349(9059):1133-6.

MacLeod MJ, Lee WK, Devlin AM, Caslake M, Anderson NH, Packard CJ, Dominiczak MH, Reid JL, Dominiczak AF.
Sodium-lithium countertransport, sodium-hydrogen exchange and membrane microviscosity in patients with hyperlipidaemia.
Clin Sci (Lond). 1997 Mar;92(3):237-46.

Clark JS, Jeffs B, Davidson AO, Lee WK, Anderson NH, Bihoreau MT, Brosnan MJ, Devlin AM, Kelman AW, Lindpaintner K, Dominiczak AF.
Quantitative trait loci in genetically hypertensive rats. Possible sex specificity.
Hypertension. 1996 Nov;28(5):898-906.

Arribas SM, Gordon JF, Daly CJ, Dominiczak AF, McGrath JC. Confocal microscopic characterization of a lesion in a cerebral vessel of the stroke-prone spontaneously hypertensive rat.
Stroke. 1996 Jun;27(6):1118-22; discussion 1122-3.

Harrap SB, Dominiczak AF, Fraser R, Lever AF, Morton JJ, Foy CJ, Watt GC.
Plasma angiotensin II, predisposition to hypertension, and left ventricular size in healthy young adults.
Circulation. 1996 Mar 15;93(6):1148-54.

Dominiczak AF, Bohr DF.
Nitric oxide and hypertension in 1995.
Curr Opin Nephrol Hypertens. 1996 Mar;5(2):174-80.

Dominiczak AF, Devlin AM, Lee WK, Anderson NH, Bohr DF, Reid JL.
Vascular smooth muscle polyploidy and cardiac hypertrophy in genetic hypertension.
Hypertension. 1996 Mar;27(3 Pt 2):752-9.